Why NMN Signal Care
When skin condition declines, skin begins to look tired.
VODA DERM NMN System is designed to support NMN-based skin vitality signals for tired-looking skin conditions. The first step of skin vitality care begins not with simple supplementation, but with preparing the flow of skin condition.

- 01
Low Vitality
Skin condition that needs a vitality signal
- 02
Dull Impression
Skin that needs a clearer, refined look
- 03
Uneven Texture
Skin that appears unbalanced and less refined
- 04
Reduced Elasticity
Skin that needs an energized-looking impression
The NAD+ Signal
Why NAD+ Signal Matters
NAD+ is a coenzyme that supports cellular energy metabolism and skin homeostasis. As skin ages, NAD+ levels decline — acting as the underlying factor behind reduced skin vitality.
VODA DERM NMN System is designed around three core roles of NAD+ in skin biology:
Cellular Energy Metabolism
Supports mitochondrial energy metabolism to help awaken the energy flow of skin cells
Damage-Repair Pathway
Supports DNA repair pathways, helping the skin's natural defense against oxidative stress
Sirtuin Pathway
Supports aging-related sirtuin pathways, contributing to skin density and resilience
The above descriptions refer to the general characteristics of NAD+ and NMN as ingredients and do not represent the direct clinical efficacy of the finished product.

NMN & NAD+ Dual Pathway
Designed Around the NMN → NAD+ Signal
NMN is one of the most direct key precursors for NAD+ biosynthesis — converted into NAD+ in a single step by NMNAT enzymes to help initiate the skin vitality signal.
VODA DERM NMN System combines direct NAD+ support with NMN-driven intracellular synthesis, designed for immediate and sustained vitality support.
Supports direct NAD+-related vitality signaling
Supports intracellular NAD+ biosynthesis
Designed for immediate + sustained vitality support


4-Step NMN Signal Conditioning System
A 4-step signal system designed to begin with NMN and shape the flow of skin vitality.
STEP 01
ACTIVATE
NMN → NAD+ Vitality Pathway
Supports a skin vitality pathway from NMN to NAD+.
STEP 02
COMMUNICATE
Grape Phyto-Exosome Signal
Grape-derived Phyto-Exosome support for skin-conditioning signals.
STEP 03
ENERGIZE
Energy Co-Factor Support
Supportive design with Coenzyme A, Thiamine Diphosphate, and Inositol.
STEP 04
REFINE
Bio-Polypeptide Conditioning
Skin impression refinement with 5 types of sh-Polypeptides.

Phyto-Exosome Delivery
Grape Phyto-Exosome Signal
VODA DERM has established an active delivery system utilizing grape callus-derived Phyto-Exosomes to help improve the transdermal delivery of NMN. This system is designed to function as an intercellular signaling mediator to support homeostasis in the dermal microenvironment.
Size — Nano-Scale
50–150nm natural lipid bilayer structure, designed for skin barrier penetration
Cargo — Bioactive Signal
Encapsulates proteins and antioxidant phytochemicals to help activate cellular signal networks
Safety — Low Immunogenicity
Significantly lower immunogenicity compared to mammalian exosomes, designed to minimize immune response
Source — Grape Callus
Plant stem cell extraction technology concentrates active ingredients into exosomes to support absorption
The above descriptions refer to the general characteristics of Phyto-Exosomes as an ingredient type and do not represent the direct clinical efficacy of the finished product.
Bio-Polypeptide Complex
5-Polypeptide Conditioning
Following activation and energy support via NMN, VODA DERM NMN System incorporates 5 types of recombinant sh-Polypeptides designed to support the epidermal and dermal physical structures for a smoother skin condition.


- sh-Polypeptide-7
hGH Fragment
Cell growth & regeneration signal
- sh-Polypeptide-5
TGF-β3 Analog
Cell differentiation & ECM remodeling
- sh-Polypeptide-4
SCF Analog
Stem cell activation & epidermal renewal
- sh-Polypeptide-2
IGF-1 Analog
Collagen & elastin synthesis support
- sh-Polypeptide-16
BMP-2 Analog
Dermal structure refinement & signaling
VODA DERM
NMN System
NMN Signal Starter System
4
Main Composition
NMN NAD+ Grape Phyto-Exosome 5 types of sh-Polypeptides
3 mL
Per Vial
×10
Vials / Box

